870 research outputs found

    Use of ERTS-1 data for regional planning in the Metropolitan Washington Council of Governments: A short brief

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    Land use and land use activity changes over discrete intervals of time represent basic data requirements in regional planning studies. Two examples of land use analysis required by the Council of Governments' transportation planning staff are described. Both were undertaken utilizing remote sensing imagery analysis. One study using large scale aircraft imagery developed a high degree of analytical detail and functional identification. The other, to support further detailed data base evaluation, utilizing ERTS-1 and small scale aircraft imagery, developed data identifying in more general detail major activity changes within the metropolitan region

    Land use determination by remote sensor analysis

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    A land use analysis of 18 selected census tracts in the Metropolitan Washington area using aerial photography was undertaken. A comparison of the results was made with comparable land use data from the Metropolitan Washington Council of Governments' Parcel File, and the results reported. Summary conclusions and recommendations for the use of photo-derived data in land use studies by COG are made

    Benefits from remote sensing data utilization in urban planning processes and system recommendations

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    The benefits of utilizing remote sensor data in the urban planning process of the Metropolitan Washington Council of Governments are investigated. An evaluation of sensor requirements, a description/ comparison of costs, benefits, levels of accuracy, ease of attainment, and frequency of update possible using sensor versus traditional data acquisition techniques are discussed

    An assessment of remote sensor imagery in the determination of housing quality data

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    Selected census tracts in the metropolitan Washington area were examined using varying scales of aerial photography. Observable characteristics of housing and neighborhoods were assessed to determine feasibility of providing data on housing stock and quality and neighborhood condition from the imagery. Small scale imagery is shown to be of relatively marginal value in providing much of the data in the detail required, but can be useful for general survey purposes

    Remote sensing project

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    The accomplishments and publications developed during the study are summarized. They illustrated a series of practical applications of remote sensing data to the urban-regional planning processes in the metropolitan Washington area

    Effectiveness of Strength Training Programs at Decreasing Upper Extremity Injury Rates in Youth Baseball Players: A Critically Appraised Topic

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    Incidence of both youth sport specialization and overuse injuries continue to rise. Baseball is a common sport where sport specialization begins in young adolescents. Youth baseball players are subject to increased risk of overuse injuries due to a combination of factors including skeletal immaturity, lack of proper biomechanics, and the heavy workloads in youth elite-level sports. Injury prevention guidelines exist, including recommendations for pitch counts and inning limits for youth baseball pitchers, as a means to reduce injury risk. However, current guidelines fail to address the need for prevention programs focusing on a variety of aspects including balance, flexibility, and strength. Focused Clinical Question: Does implementing a strength training program in youth baseball players decrease their risk of sustaining an upper extremity injury compared to players who don’t complete a strengthening program

    An examination of applications of remote sensing data to Metropolitan Washington Council of Governments' planning requirements

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    A comprehensive inventory of a series of remote sensing applications for a variety of regional planning programs in metropolitan Washington was undertaken. Examples of application, methods for data utilization, and corresponding photographic illustrations are provided illustrating how remote sensing would prove particularly useful as a unique and/or supplemental data source

    Three-dimensional structural modelling and calculation of electrostatic potentials of HLA Bw4 and Bw6 epitopes to explain the molecular basis for alloantibody binding: toward predicting HLA antigenicity and immunogenicity.

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    BACKGROUND: We have previously shown that qualitative assessment of surface electrostatic potential of HLA class I molecules helps explain serological patterns of alloantibody binding. We have now used a novel computational approach to quantitate differences in surface electrostatic potential of HLA B-cell epitopes and applied this to explain HLA Bw4 and Bw6 antigenicity. METHODS: Protein structure models of HLA class I alleles expressing either the Bw4 or Bw6 epitope (defined by sequence motifs at positions 77 to 83) were generated using comparative structure prediction. The electrostatic potential in 3-dimensional space encompassing the Bw4/Bw6 epitope was computed by solving the Poisson-Boltzmann equation and quantitatively compared in a pairwise, all-versus-all fashion to produce distance matrices that cluster epitopes with similar electrostatics properties. RESULTS: Quantitative comparison of surface electrostatic potential at the carboxyl terminal of the α1-helix of HLA class I alleles, corresponding to amino acid sequence motif 77 to 83, produced clustering of HLA molecules in 3 principal groups according to Bw4 or Bw6 epitope expression. Remarkably, quantitative differences in electrostatic potential reflected known patterns of serological reactivity better than Bw4/Bw6 amino acid sequence motifs. Quantitative assessment of epitope electrostatic potential allowed the impact of known amino acid substitutions (HLA-B*07:02 R79G, R82L, G83R) that are critical for antibody binding to be predicted. CONCLUSIONS: We describe a novel approach for quantitating differences in HLA B-cell epitope electrostatic potential. Proof of principle is provided that this approach enables better assessment of HLA epitope antigenicity than amino acid sequence data alone, and it may allow prediction of HLA immunogenicity.This is the author accepted manuscript. The final version is available from Wolters Kluwer via http://dx.doi.org/10.1097/TP.000000000000054

    Free volume dilatation in polymers by ortho-positronium

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    The possibility of positronium induced free volume cavity expansion in some polymers above the glass transition temperature was investigated using experimental positron annihilation lifetime data from the literature for polydimethylsiloxane, polyisobutylene, and polybutadiene as function of temperature. The results suggest that free volume sites can expand towards an equilibrium size, determined as the equilibrium Ps-bubble size defined earlier for low-molecular-weight liquids. The expansion can be explained by the increase of molecular mobility and hence decrease of relaxation times, which at the higher temperatures approach the o-Ps lifetimes. Nanoscale viscosities were estimated using Navier-Stokes equation and were found to be several orders of magnitude lower than the macroscopic viscosity at the same temperature

    Radiation measurements in a simulated non-terrestrial atmosphere

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    A high-speed wind tunnel has been used to experimentally simulate the flow experienced by a capsule entering a planetary atmosphere. High speed photography showed that a steady test time of approximately 50 μs existed in the facility. Holographic interferometry has been performed to measure the twodimensional density distribution around a cylinder in the flow. A peak density ratio (density normalised by the free-stream density) of about 14 was observed. Emission spectroscopy allowed the characterisation of the conditions along the stagnation streamline in front of the capsule model. The results showed a temperature that varied between 8,500 K and 11,000 K in this region
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